Anti-SLC7A3 Antibody Picoband® 31.0647 Vervoeging

Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene. This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein. The International Radiation Hybrid Mapping Consortium mapped the SLC7A3 gene to the X chromosome.

Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3; SLC7A3; ATRC3, CAT3

SLC7A3

84889

Q8WY07

Human

No cross-reactivity with other proteins.

A synthetic peptide corresponding to a sequence at the C-terminus of human SLC7A3.

Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala. .

Flow Cytometry

Amino Acid Metabolism, Amino Acids, Cancer, Channels, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Liquid

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. .

1. Ito K, Groudine M (1997) . A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain.. J. Biol. Chem. 272 (42) : 26780–6. 2. Gilles W, Vulcu SD, Liewald JF, et al. (2005) . Monovalent cation conductance in Xenopus laevis oocytes expressing hCAT-3.. Biochim. Biophys. Acta.1668 (2) : 234–9. 3. Vekony, N., Wolf, S., Boissel, J.-P., Gnauert, K., Closs, E. I. Human cationic amino acid transporter hCAT-3 is preferentially expressed in peripheral tissues. Biochemistry 40: 12387-12394, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

67169 MW

6

Cationic amino acid transporter 3

Cell membrane; Multi-pass membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.