Anti-SLD5/GINS4 Antibody Picoband® 0,00647 Vervoeging

The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610) . The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]) . See GINS1 for additional information about the GINS complex.

GINS4

84296

Q9BRT9

Human, Mouse, Rat

E.coli-derived human SLD5/GINS4 recombinant protein (Position: M1-I223) . Human GINS4 shares 87.9% and 88.8% amino acid (aa) sequence identity with mouse and rat GINS4, respectively.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Kong, L., Ueno, M., Itoh, M., Yoshioka, K., Takakura, N. Identification and characterization of mouse PSF1-binding protein, SLD5. Biochem. Biophys. Res. Commun. 339: 1204-1207, 2006. 2. Takayama, Y., Kamimura, Y., Okawa, M., Muramatsu, S., Sugino, A., Araki, H. GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev. 17: 1153-1165, 2003. 3. Ueno, M., Itoh, M., Kong, L., Sugihara, K., Asano, M., Takakura, N. PSF1 is essential for early embryogenesis in mice. Molec. Cell Biol. 25: 10528-10532, 2005.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

26 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.