Anti-SLITRK1 Antibody Picoband®

SLITRK1 (SLIT and NTRK-like family, member 1) is a human gene that codes for a transmembrane and signalling protein that is part of the SLITRK gene family, which is responsible for synapse regulation and presynaptic differentiation in the brain. This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. However, the protein encoded by this gene lacks the region of homology to neurotrophin receptors. This protein is thought to be involved in neurite outgrowth. Mutations in this gene may be associated with Tourette syndrome. Alternative splicing results in multiple transcript variants.

Boster Bio Anti-SLITRK1 Antibody Picoband® catalog # A07507-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

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SLITRK1

114798

Q96PX8

Human

No cross reactivity with other proteins.

E.coli-derived human SLITRK1 recombinant protein (Position: D22-D696) . Human SLITRK1 shares 97.5% amino acid (aa) sequence identity with mouse SLITRK1.

Expressed in all tissues.

WB, Flow Cytometry, ELISA

Signal Transduction, Signaling Pathway, Small G Proteins

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Abelson, J. F., Kwan, K. Y., O'Roak, B. J., Baek, D. Y., Stillman, A. A., Morgan, T. M., Mathews, C. A., Pauls, D. L., Rasin, M.-R., Gunel, M., Davis, N. R., Gulhan Ercan-Sencicek, A., and 12 others. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310: 317-320, 2005. 2. Aruga, J., Mikoshiba, K. Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Molec. Cell. Neurosci. 24: 117-129, 2003. 3. Aruga, J., Yokota, N., Mikoshiba, K. Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue. Gene 315: 87-94, 2003.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A07507-2

52588 MW

55 kDa

6

Serine/threonine-protein kinase AtPK1/AtPK6

Cytoplasm. Nucleus.

Serine/threonine-protein kinase AtPK1/AtPK6

IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.