Anti-SMAP1 Antibody Picoband® 0,00647 Vervoeging

Stromal membrane-associated protein 1 is a protein that in humans is encoded by the SMAP1 gene. The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms.

Interleukin-17B; IL-17B; Cytokine CX1; Cytokine-like protein ZCYTO7; Neuronal interleukin-17-related factor; Il17b; Nirf, Zcyto7

SMAP1

60682

Q8IYB5

Human

No cross-reactivity with other proteins.

E.coli-derived human SMAP1 recombinant protein (Position: K126-Q416) .

Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Flow Cytometry

Cytokines, Immunology, Innate Immunity, Interleukins

Immunogen affinity purified.

Liquid

Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. .

1. Kobayashi, N., Kon, S., Henmi, Y., Funaki, T., Satake, M., Tanabe, K. The Arf GTPase-activating protein SMAP1 promotes transferrin receptor endocytosis and interacts with SMAP2. Biochem. Biophys. Res. Commun. 453: 473-479, 2014. 2. Marcos, I., Borrego, S., Rodriguez de Cordoba, S., Galan, J. J., Antinolo, G. Cloning, characterization and chromosome mapping of the human SMAP1 gene. Gene 292: 167-171, 2002. 3. Sato, Y., Hong, H. N., Yanai, N., Obinata, M. Involvement of stromal membrane-associated protein (SMAP-1) in erythropoietic microenvironment. J. Biochem. 124: 209-216, 1998.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Interleukin 17B

Secreted.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.