Anti-SMYD3 Monoklonale antilichamen

Boster Bio Anti-SMYD3 Monoclonal Antibody catalog # M02080. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321; F11R; JAM1, JCAM; UNQ264/PRO301

SMYD3

64754

Q9H7B4

Human, Mouse, Rat

A synthesized peptide derived from human SMYD3 Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.

Clone: ADHE-19

Predominantly in urogenital tissues.

WB, IHC, ICC, IF, IP, Flow Cytometry

Cancer, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Methylation, Oncoproteins, Oncoproteins/Suppressors, Pol II Transcription, Polymerase Associated Factors, Transcription, Transcription Factors

Affinity-chromatography

0.5mg/ml

Liquid

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity) . Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02080

32583 MW

29 kDa

Junctional adhesion molecule A

Cell junction, tight junction . Cell membrane ; Single-pass type I membrane protein . Localized at tight junctions of both epithelial and endothelial cells.

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.