Anti-Solo/SETD1 Antibody Picoband® fluoro594 Vervoeging

SEC14 and spectrin domains 1, also known as SEC14 domain and spectrin repeat-containing protein 1 and Solo, is a protein that in humans is encoded by the SESTD1 gene. Enables phosphatidylinositol-3,4-bisphosphate binding activity and phospholipid binding activity. Involved in negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Located in intermediate filament cytoskeleton. Colocalizes with calcium channel complex.

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

SESTD1

91404

Q86VW0

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human Solo/SESTD1 recombinant protein (Position: Q549-E690) .

Brain. Expression restricted to astrocytes.

Flow Cytometry

Channels, Metabolism, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Liquid

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

1. Miehe, S. , Bieberstein, A. , Arnould, I. , Ihdene, O. , Rutten, H. , & Strubing, C. . (2010) . The phospholipid-binding protein sestd1 is a novel regulator of the transient receptor potential channels trpc4 and trpc5. Journal of Biological Chemistry, 285 (16), 12426.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

29370 MW

6

NOVA alternative splicing regulator 2

Nucleus.

Aquaporin-6

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.