Anti-Somatostatine/SST Antilichaam Picoband®

SST (Somatostatin), also known as SMST, is a peptide hormone. Naylor et al. (1983) assigned the somatostatin gene to chromosome 3 by analyzing somatic cell hybrids with a polymorphic gene probe. Yacubova and Komuro (2002) examined the effects of somatostatin in cerebellar granule cells of early postnatal mice, because these cells express all 5 types of somatostatin receptors before the initiation of their migration. Saito et al. (2005) found that somatostatin modulated the proteolytic degradation of beta-amyloid catalyzed by neprilysin both in vitro and in vivo.

Boster Bio Anti-Somatostatin/SST Antibody catalog # PA2054. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Somatostatin; Growth hormone release-inhibiting factor; Somatostatin-28; Somatostatin-14; SST

SST

6750

P61278

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin, identical to the related rat and mouse sequences.

Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. .

IHC, WB

DNA/RNA, DNA Damage & Repair, DNA Damage Response, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Nucleotide Metabolism, Oncoproteins/Suppressors, p53 Pathway, Pathways and Processes, Tumor Suppressors

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Somatostatin inhibits the release of somatotropin.

1. Naylor, S. L., Sakaguchi, A. Y., Shen, L.-P., Bell, G. I., Rutter, W. J., Shows, T. B. Polymorphic human somatostatin gene is located on chromosome 3. Proc. Nat. Acad. Sci. 80: 2686-2689, 1983. 2. Saito, T., Iwata, N., Tsubuki, S., Takaki, Y., Takano, J., Huang, S.-M., Suemoto, T., Higuchi, M., Saido, T. C. Somatostatin regulates brain amyloid beta-peptide A-beta-42 through modulation of proteolytic degradation. Nature Med. 11: 434-439, 2005. 3. Yacubova, E., Komuro, H. Stage-specific control of neuronal migration by somatostatin. Nature 415: 77-81, 2002.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PA2054

12736 MW

83 kDa

No cross reactivity with other proteins.

Somatostatin

Secreted.

Belongs to the somatostatin family.

Somatostatin

Rabbit IgG

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.