Anti-sperm-geassocieerde antigen 8 SPAG8 Antilichaam

Boster Bio Anti-Sperm-associated antigen 8 SPAG8 Antibody catalog # A10518. Tested in WB, IHC applications. This antibody reacts with Mouse, Rat.

Sperm-associated antigen 8; HSD-1; Sperm membrane protein 1; SMP-1; Sperm membrane protein BS-84; SPAG8

SPAG8

Q99932

Mouse, Rat

Recombinant fusion protein of human SPAG8 (NP_758516.1) .

Expressed in testis (germ cells), but not in liver, kidney, prostate and small intestine.

WB, IHC

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5-regulated transcriptional activation of CREM isoform tau (By similarity) . Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity) . Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis (PubMed:19548270) . May play a role in fertility and microtubule formation through interaction with RANBP9 (PubMed:10500252) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A10518

44819 MW

Sperm-associated antigen 8

Cytoplasm

Sperm-associated antigen 8

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2