Anti-SPOCK3 Antibody Picoband® fluoro488 Vervoeging

This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene

B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD272; BTLA

SPOCK3

50859

Q9BQ16

Human

No cross-reactivity with other proteins.

E.coli-derived human SPOCK3 recombinant protein (Position: Q104-H396) .

Wide tissue distribution (highest in the pancreas and very low in brain) . Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.

Flow Cytometry

Adaptive Immunity, Immunology, T Cells

Immunogen affinity purified.

Liquid

Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.

1. Nakada, M., Yamada, A., Takino, T., Miyamori, H., Takahashi, T., Yamashita, J., Sato, H. Suppression of membrane-type 1 matrix metalloproteinase (MMP) -mediated MMP-2 activation and tumor invasion by testican 3 and its splicing variant gene product, N-Tes. Cancer Res. 61: 8896-8902, 2001. 2. Vannahme, C., Schubel, S., Herud, M., Gosling, S., Hulsmann, H., Paulsson, M., Hartmann, U., Maurer, P. Molecular cloning of testican-2: defining a novel calcium-binding proteoglycan family expressed in brain. J. Neurochem. 73: 12-20, 1999.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

65411 MW

6

B and T lymphocyte associated

Membrane.

Glutamate decarboxylase 2

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.