Anti-SPRY3 Antibody Picoband® APC-vervoeging

Involved in negative regulation of MAPK cascade. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol.

SPRY3; Protein sprouty homolog 3; Spry-3

SPRY3

10251

O43610

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human SPRY3 recombinant protein (Position: M1-R162) . Human SPRY3 shares 91.4% amino acid (aa) sequence identity with mouse SPRY3.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. De Bonis, M. L., Cerase, A., Matarazzo, M. R., Ferraro, M., Strazzullo, M., Hansen, R. S., Chiurazzi, P., Neri, G., D'Esposito, M. Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications. Hum. Molec. Genet. 15: 1123-1132, 2006. 2. Hacohen, N., Kramer, S., Sutherland, D., Hiromi, Y., Krasnow, M. A. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 92: 253-263, 1998. 3. Ross, M. T., Grafham, D. V., Coffey, A. J., Scherer, S., McLay, K., Muzny, D., Platzer, M., Howell, G. R., Burrows, C., Bird, C. P., Frankish, A., Lovell, F. L., and 270 others. The DNA sequence of the human X chromosome. Nature 434: 325-337, 2005.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

31 kDa

6

Sprouty RTK signaling antagonist 3

Protein sprouty homolog 3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.