Anti-SQRDL/SQOR Antibody Picoband® fluoro488 Vervoeging

The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein.

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

SQOR

58472

Q9Y6N5

Human

No cross reactivity with other proteins.

E.coli-derived human SQRDL/SQOR recombinant protein (Position: R12-E321) . Human SQOR shares 86.1% amino acid (aa) sequence identity with mouse SQOR.

Expressed in all tissues.

Flow Cytometry

Signal Transduction, Signaling Pathway, Small G Proteins

Immunogen affinity purified.

Liquid

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

1. Friederich, M. W., Elias, A. F., Kuster, A., Laugwitz, L., Larson, A. A., Landry, A. P., Ellwood-Digel, L., Mirsky, D. M., Dimmock D., Haven, J., Jiang, H., MacLean, K. N., Styren, K., Schoof, J., Goujon, L., Lefrancois, T., Friederich, M., Couglin, C. R., II, Banerjee, R., Haack, T. B., Van Hove, J. L. K. Pathogenic variants in SQOR encoding sulfide:quinone oxidoreductase are a potentially treatable cause of Leigh disease. J. Inherit. Metab. Dis. 43: 1024-1036, 2020. 2. Gonzalez-Garcia, P., Hidalgo-Gutierrez, A., Mascaraque, C., Barriocanal-Casado, E., Bakkali, M., Ziosi, M., Abdihankyzy, U. B., Sanchez-Hernandez, S., Escames, G., Prokish, H., Martin, F., Quinzii, C. M., Lopez, L. C. Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism. Hum. Molec. Genet. 29: 3296-3311, 2020. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 09/01/2017.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

52588 MW

6

Serine/threonine-protein kinase AtPK1/AtPK6

Cytoplasm. Nucleus.

Serine/threonine-protein kinase AtPK1/AtPK6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.