Anti-SRPRA Antibody Picoband® 31.0550 Vervoeging

The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.

Mitochondrial import inner membrane translocase subunit Tim17-A; Inner membrane preprotein translocase Tim17a; TIMM17A; MIMT17; TIM17; TIM17A; TIMM17

SRPRA

6734

P08240

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human SRPRA recombinant protein (Position: R346-A638) .

Flow Cytometry

Cancer, Metabolism, Mitochondrial Metabolism, Organelle Proteins, Pathways and Processes, Protein Trafficking, Signal Transduction, Tumor Biomarkers

Immunogen affinity purified.

Liquid

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

1. Hortsch, M., Labeit, S., Meyer, D. I. Complete cDNA sequence coding for human docking protein. Nucleic Acids Res. 16: 361-362, 1988. 2. Janin, N., Delattre, O., Lipinski, M. PCR-assisted localization of the human SRPR gene. Hum. Genet. 88: 583-585, 1992. 3. Pool, M. R., Stumm, J., Fulga, T. A., Sinning, I., Dobberstein, B. Distinct modes of signal recognition particle interaction with the ribosome. Science 297: 1345-1348, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Translocase of inner mitochondrial membrane 17A

Mitochondrion inner membrane, Multi-pass membrane protein.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.