Anti-SSR3 Antibody Picoband® 31.0550 Vervoeging

SSR3 (signal sequence receptor, gamma) is also known as TRAPG. By immunoaffinity chromatography, biochemical purification, peptide sequence analysis, and screening of a rat liver cDNA library, Hartmann et al. (1993) obtained a cDNA encoding Ssr3, which they termed Trap-gamma. The deduced 185-amino acid protein spans the membrane 4 times and is expressed as a 20-kD protein. Gross (2012) mapped the SSR3 gene to chromosome 3q25.31 based on an alignment of the SSR3 sequence with the genomic sequence (GRCh37) . Hartmann et al. (1993) found that Ssr3 was associated in equal amounts with Ssr1, Ssr2, and Ssr4 in canine pancreatic microsomes.

Translocon-associated protein subunit gamma; TRAP-gamma; Signal sequence receptor subunit gamma; SSR-gamma; SSR3; TRAPG

SSR3

6747

Q9UNL2

Human, Monkey, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the N-terminus of human SSR3, identical to the related rat and mouse sequences.

Highly expressed in the brain, lung, kidney and heart. Expressed at low levels in the liver and spleen. .

Flow Cytometry

Calcium Binding Proteins, Calcium Signaling, DNA/RNA, Epigenetics and Nuclear Signaling, ER Proteins, Organelle Proteins, Protein Trafficking, Signal Transduction, Signaling Pathway, Translation

Immunogen affinity purified.

Liquid

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

1. Gross, M. B.Personal Communication.Baltimore, Md. 6/20/2012. 2. Hartmann, E., Gorlich, D., Kostka, S., Otto, A., Kraft, R., Knespel, S., Burger, E., Rapoport, T. A., Prehn, S.A tetrameric complex of membrane proteins in the endoplasmic reticulum.Europ. J. Biochem. 214: 375-381, 1993.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

21080 MW

No cross reactivity with other proteins.

6

Translocon-associated protein subunit gamma

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Translocon-associated protein subunit gamma (TRAP-gamma)

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.