Anti-ST6GALNAC2 Antibody Picoband® fluoro647 Vervoeging

Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 is an enzyme that in humans is encoded by the ST6GALNAC2 gene. ST6GALNAC2 belongs to a family of sialyltransferases that add sialic acids to the nonreducing ends of glycoconjugates. At the cell surface, these modifications have roles in cell-cell and cell-substrate interactions, bacterial adhesion, and protein targeting.

Pre T-cell antigen receptor alpha; pT-alpha; pTa; pT-alpha-TCR; PTCRA

ST6GALNAC2

10610

Q9UJ37

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human ST6GALNAC2 recombinant protein (Position: Q32-R374) .

Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Flow Cytometry

Hematopoietic Progenitors, Lymphoid, Stem Cells, T Lymphocytic Lineage

Immunogen affinity purified.

Liquid

The pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) regulates early T-cell development. .

1. Samyn-Petit, B., Krzewinski-Recchi M.-A., Steelant, W. F. A., Delannoy, P., Harduin-Lepers, A. Molecular cloning and functional expression of human ST6GalNAc II: molecular expression in various human cultured cells. Biochim. Biophys. Acta 1474: 201-211, 2000. 2. Sotiropoulou, G., Kono, M., Anisowicz, A., Stenman, G., Tsuji, S., Sager, R. Identification and functional characterization of a human GalNAc alpha-2,6-sialyltransferase with altered expression in breast cancer. Molec. Med. 8: 42-55, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

41409 MW

6

Pre T cell antigen receptor alpha

Membrane; Single-pass type I membrane protein.

Protein NDRG3

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.