Anti-ST8SIA2 Antibody Picoband® fluoro647 Vervoeging

Alpha-2,8-sialyltransferase 8B is an enzyme that in humans is encoded by the ST8SIA2 gene. The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1) . This protein is a member of glycosyltransferase family 29.

Troponin T, fast skeletal muscle; TnTf; Beta-TnTF; Fast skeletal muscle troponin T; fTnT; TNNT3

ST8SIA2

8128

Q92186

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human ST8SIA2 recombinant protein (Position: D69-R267) .

In fetal and adult fast skeletal muscles, with a higher level expression in fetal than in adult muscle.

Flow Cytometry

Golgi Proteins, Organelles, Protein Trafficking, Signal Transduction, Subcellular Markers

Immunogen affinity purified.

Liquid

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

1. Angata, K., Long, J. M., Bukalo, O., Lee, W., Dityatev, A., Wynshaw-Boris, A., Schachner, M., Fukuda, M., Marth, J. D. Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that s hippocampal axonal targeting and promotes fear behavior. J. Biol. Chem. 279: 32603-32613, 2004. 2. Angata, K., Nakayama, J., Fredette, B., Chong, K., Ranscht, B., Fukuda, M. Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule: tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST. J. Biol. Chem. 272: 7182-7190, 1997. 3. Angata, K., Suzuki, M., McAuliffe, J., Ding, Y., Hindsgaul, O., Fukuda, M. Differential biosynthesis of polysialic acid on neural cell adhesion molecule (NCAM) and oligosaccharide acceptors by three distinct alpha-2,8-sialyltransferases, ST8Sia IV (PST), ST8Sia II (STX), and ST8Sia III. J. Biol. Chem. 275: 18594-18601, 2000.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Troponin T3, fast skeletal type

Troponin complex. Cytosol.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.