Anti-STEAP2 Antilichaam

Anti-STEAP2 Antibody (AZD0516 antibody) is a selective six-transmembrane epithelial antigen of prostate 2 (STEAP2) inhibitor. Anti-STEAP2 Antibody inhibits the proliferation, migration and invasion of prostate cancer cells by blocking the STEAP2-mediated ERK/MAPK signaling pathway. Anti-STEAP2 Antibody is promising for research of prostate cancer[1][2].

AZD0516 antibody

12352203

ERK; p38 MAPK

MAPK/ERK Pathway; Stem Cell/Wnt

Cancer-Kinase/protease

Cancer

99.65

[Anti-STEAP2Antibody]

(147.34 kDa)

[1]Jones LA, et al. Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer. Cell Mol Biol (Noisy-le-grand) . 2023 Apr 30;69 (4) :179-187.|[2]Zanvit P, et al. Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer. J Clin Invest. 2023 Nov 15;133 (22) :e169655.

Dry Ice

Store at -80°C for 2 years

http://file.medchemexpress.com/batch_PDF/HY-P991503/Anti-STEAP2-Antibody-SDS-MedChemExpress.pdf

Inhibitory Antibodies

No Development Reported