Anti-STK36 Antilichaam

Boster Bio Anti-STK36 Antibody catalog # A09526. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Serine/threonine-protein kinase 36;2.7.11.1; Fused homolog; STK36

STK36

Q9NRP7

Human, Mouse, Rat

Synthetic peptide, corresponding to amino acids380-430 of Human STK36.

Expressed at low levels in most fetal tissues, adult ovaries and at high levels in adult testis, where it is localized in germ cells.

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483) . Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483) . GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483) . Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity) . Essential for construction of the central pair apparatus of motile cilia.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09526

143995 MW

WB: 1:500-1:1000

Serine/threonine-protein kinase 36

Cytoplasm

Serine/threonine-protein kinase 36

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2