Anti-STMN3 Antibody Picoband® 0,00647 Vervoeging

Stathmin-3 is a protein that in humans is encoded by the STMN3 gene. This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants.

Annexin A8 ; Annexin VIII ; Annexin-8 ; Vascular anticoagulant-beta ; VAC-beta ; ANXA8 ; ANX8

STMN3

50861

Q9NZ72

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human STMN3 recombinant protein (Position: F25-H156) .

Ubiquitously expressed.

Flow Cytometry

Signal Transduction, Cardiovascular, Cytoskeleton, Cytoskeleton/ECM, Actin Binding Proteins, Actin, etc., Microfilaments, Cell Adhesion

Immunogen affinity purified.

Liquid

This protein is an anticoagulant protein that acts as an in inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

1. Bieche, I., Maucuer, A., Laurendeau, I., Lachkar, S., Spano, A. J., Frankfurter, A., Levy, P., Manceau, V., Sobel, A., Vidaud, M., Curmi, P. A. Expression of stathmin family genes in human tissues: non-neural-restricted expression for SCLIP. Genomics 81: 400-410, 2003. 2. Gavet, O., Ozon, S., Manceau, V., Lawler, S., Curmi, P., Sobel, A. The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network. J. Cell Sci. 111: 3333-3346, 1998. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 12/23/2003.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

36881 MW

6

Annexin A8

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Annexin A8

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.