Anti-STON2 Antibody Picoband® 31.0550 Vervoeging

This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene.

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

STON2

85439

Q8WXE9

Human

No cross-reactivity with other proteins.

E.coli-derived human STON2 recombinant protein (Position: L4-K855) .

Brain. Expression restricted to astrocytes.

Flow Cytometry

Channels, Metabolism, Plasma Membrane, Signal Transduction

Immunogen affinity purified.

Liquid

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

1. Martina, J. A., Bonangelino, C. J., Aguilar, R. C., Bonifacino, J. S. Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery. J. Cell. Biol. 153: 1111-1120, 2001. 2. Walther, K., Krauss, M., Diril, M. K., Lemke, S., Ricotta, D., Honing, S., Kaiser, S., Haucke, V. Human stoned B interacts with AP-2 and synaptotagmin and facilitates clathrin-coated vesicle uncoating. EMBO Rep. 2: 634-640, 2001. Note: Erratum: EMBO Rep. 3: 197 only, 2002.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

29370 MW

6

NOVA alternative splicing regulator 2

Nucleus.

Aquaporin-6

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.