Anti-STPG2 Antibody Picoband® 31.0550 Vervoeging

STPG2 (sperm tail PG rich repeat containing 2) is a 459 amino acid protein that contains 9 STPGR (sperm-tail PG-rich) repeats in human, and a 561 amino acid protein containing 10 STPGR (sperm-tail PG-rich) repeats in mouse. The gene encoding STPG2 maps to human chromosome 4q22.3 and mouse chromosome 3 H1. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington’s disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.

Placenta-specific protein 9; PLAC9

STPG2

285555

Q8N412

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human STPG2 recombinant protein (Position: N39-D399) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Flow Cytometry

Cell Biology, Cell Type Markers, Tags & Cell Markers

Immunogen affinity purified.

Liquid

Involved in cellular response to oxidative stress.

1. Yakut, S. , Cetin, Z. , Clark, O. A. , Usta, M. F. , Berker, S. , & Luleci, G. . (2013) . Exceptional complex chromosomal rearrangement and microdeletions at the 4q22.3q23 and 14q31.1q31.3 regions in a patient with azoospermia. Gene, 512 (1), 157-160. 2. Jing, J. , Fridley, B. L. , Feng, Q. , Abo, R. P. , Abra, B. , & Anthony, B. , et al. (2013) . Genome-wide association study for biomarker identification of rapamycin and everolimus using a lymphoblastoid cell line system. Frontiers in Genetics, 4, 166-166. 3. Lamesch, P. , Li, N. , Milstein, S. , Fan, C. , & Tong, H. . (2007) . Horfeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics, 89 (3), 307-315.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

24145 MW

6

Placenta specific 9

Secreted.

Transmembrane protein 240

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.