Anti-Stromelysin-2 MMP10 Antibody Picoband®

Stromelysin-2 also known as matrix metalloproteinase-10 (MMP-10) or transin-2 is an enzyme that in humans is encoded by the MMP10 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Boster Bio Anti-Stromelysin-2 MMP10 Antibody catalog # PA1380. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Stromelysin-2; SL-2;3.4.24.22; Matrix metalloproteinase-10; MMP-10; Transin-2; MMP10; STMY2

MMP10

4319

P09238

Human

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human MMP10.

WB

Angiogenesis, Cancer, Cardiovascular, Cell Biology, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metalloprotease, Proteolysis/Ubiquitin, Proteolytic Enzymes

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.

1. Muller D, Quantin B, Gesnel MC, Millon-Collard R, Abecassis J, Breathnach R (July 1988) . The collagenase gene family in humans consists of at least four members. Biochem. J. 253 (1) : 187–92. 2. Jung JY, Warter S, Rumpler Y (1990) . Localization of stromelysin 2 gene to the q22.3-23 region of chromosome 11 by in situ hybridization. Ann. Genet. 33 (1) : 21–3.

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=PA1380

54151 MW

90 kDa

No cross reactivity with other proteins.

Stromelysin-2

Secreted, extracellular space, extracellular matrix .

Belongs to the peptidase M10A family.

Stromelysin-2 (SL-2)

Rabbit IgG

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.