Anti-Sumo2/3 Konijn Monoklonale Antilichaam

Boster Bio Anti-Sumo2/3 Rabbit Monoclonal Antibody catalog # M01282-2. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Small ubiquitin-related modifier 2 ; SUMO-2 ; HSMT3 ; SMT3 homolog 2 ; SUMO-3 ; Sentrin-2 ; Ubiquitin-like protein SMT3B ; Smt3B ; SUMO2 ; SMT3B , SMT3H2

SUMO2

6613/6612

P61956/P55854

Human, Mouse, Rat

A synthesized peptide derived from human Sumo2/3

Clone: IBG-19

Broadly expressed. .

WB, IHC, ICC, IF

Adaptive Immunity, B Cells, Host-Virus Interaction, Human Protein, Immunology, Interspecies Interaction, Microbiology, Protein

Affinity-chromatography

0.5mg/ml

Liquid

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2, CBX4 or ZNF451 (PubMed:26524494) . This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins (PubMed:18408734, PubMed:18538659, PubMed:21965678, PubMed:9556629) . Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01282-2

70 kDa

Small ubiquitin-related modifier 2

Nucleus. Nucleus, PML body.

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.