Anti-SV2C Antibody Picoband®

Predicted to enable transmembrane transporter activity. Predicted to be involved in several processes, including chemical synaptic transmission; neurotransmitter transport; and regulation of synaptic vesicle exocytosis. Predicted to be located in plasma membrane and synaptic vesicle. Predicted to be active in dopaminergic synapse and synaptic vesicle membrane.

Boster Bio Anti-SV2C Antibody Picoband® catalog # A10958-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

SV2C; KIAA1054; Synaptic vesicle glycoprotein 2C

SV2C

22987

Q496J9

Human, Mouse, Rat

No cross-reactivity with other proteins

E.coli-derived human SV2C recombinant protein (Position: M1-A579) . Human SV2C shares 96.7% and 96.5% amino acid (aa) sequence identity with mouse and rat SV2C, respectively.

WB, Flow Cytometry, ELISA

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

1. Benoit, R. M., Frey, D., Hilbert, M., Kevenaar, J. T., Wieser, M. M., Stirnimann, C. U., McMillan, D., Ceska, T., Lebon, F., Jaussi, R., Steinmetz, M. O., Schertler, G. F. X., Hoogenraad, C. C., Capitani, G., Kammerer, R. A. Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A. Nature 505: 108-111, 2014. 2. Dong, M., Yeh, F., Tepp, W. H., Dean, C., Johnson, E. A., Janz, R., Chapman, E. R. SV2 is the protein receptor for botulinum neurotoxin A. Science 312: 592-596, 2006. 3. Iezzi, M., Theander, S., Janz, R., Loze, C., Wollheim, C. B. SV2A and SV2C are not vesicular Ca (2+) transporters but control glucose-evoked granule recruitment. J. Cell Sci. 118: 5647-5660, 2005.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A10958-1

82 kDa

90 kDa

6

Synaptic vesicle glycoprotein 2C

Synaptic vesicle glycoprotein 2C

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.