Anti-Synaptogyrine-3 SYNGR3 Antilichaam

Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.

Boster Bio Anti-Synaptogyrin-3 SYNGR3 Antibody (Catalog # A14692) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Synaptogyrin-3

SYNGR3

O43761

Human, Mouse, Rat

SYNGR3 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SYNGR3. The immunogen is located within the last 50 amino acids of SYNGR3.

Expressed in brain and placenta.

ELISA, WB, IHC-P, IF

Neuroscience

SYNGR3 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

May play a role in regulated exocytosis. May indirectly regulate the activity of the plasma membrane dopamine transporter SLC6A3 and thereby regulate dopamine transport back from the synaptic cleft into the presynaptic terminal.

SYNGR3 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A14692

24555 MW

Synaptogyrin 3

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane

Bovine

Synaptogyrin 3

IgG

SYNGR3 Antibody is supplied in PBS containing 0.02% sodium azide.