Anti-TARS2 Antibody Picoband® 31.0550 Vervoeging

This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 4.

RNA-binding motif, single-stranded-interacting protein 3; RBMS3

TARS2

80222

Q9BW92

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human TARS2 recombinant protein (Position: Q69-F718) .

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Flow Cytometry

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, RNA Processing

Immunogen affinity purified.

Liquid

Binds poly (A) and poly (U) oligoribonucleotides.

1. Bonnefond, L., Fender, A., Rudinger-Thirion, J., Giege, R., Florentz, C., Sissler, M. Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. Biochemistry 44: 4805-4816, 2005. 2. Diodato, D., Melchionda, L., Haack, T. B., Dallabona, C., Baruffini, E., Donnini, C., Granata, T., Ragona, F., Balestri, P., Margollicci, M., Lamantea, E., Nasca, A., Powell, C. A., Minczuk, M., Strom, T. M., Meitinger, T., Prokisch, H., Lamperti, C., Zeviani, M., Ghezzi, D. VARS2 and TARS2 mutations in patients with mitochondrial encephalomyopathies. Hum. Mutat. 35: 983-989, 2014.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

RNA binding motif single stranded interacting protein 3

Cytoplasm.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.