Anti-TAX1BP3 Monoklonale Antilichaam

Boster Bio Anti-TAX1BP3 Monoclonal Antibody catalog # M05588. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Drebrin; Developmentally-regulated brain protein; DBN1; D0S117E

TAX1BP3

30851

O14907

Human, Mouse, Rat

A synthesized peptide derived from human TAX1BP3 May play a role in the Rho signaling pathway. May act as an inhibitor of the Wnt signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.

Clone: ADDC-20

Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas. Expressed in peripheral blood lymphocytes, including T-cells (at protein level) . .

WB, IHC, Flow Cytometry

Cytoplasmic, Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, G Protein Signaling, Nuclear, Regulators, Signal Transduction, Signaling Pathway, Signaling Pathways, Small G Proteins, Stem Cells, Transcription

Affinity-chromatography

0.5mg/ml

Liquid

Drebrins might play some role in cell migration, extension of neuronal processes and plasticity of dendrites. Required for actin polymerization at immunological synapses (IS) and for CXCR4 recruitment to IS. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M05588

71429 MW

14 kDa

Drebrin

Cytoplasm . Cytoplasm, cell cortex . Cell junction . Cell projection . Cell projection, growth cone . In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm. In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400) . Colocalized with DBN1, RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity) . .

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.