Anti-TEAD2 Antilichaam

Boster Bio Anti-TEAD2 Antibody catalog # A09168. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Transcriptional enhancer factor TEF-4; TEA domain family member 2; TEAD-2; TEAD2; TEF4

TEAD2

Q15562

Human, Mouse, Rat

Synthetic peptide, corresponding to amino acids 61-106 of Human TEAD2.

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'- GTGGAATGT-3') . May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A09168

49243 MW

WB: 1:500-1:1000

Transcriptional enhancer factor TEF-4

Nucleus.

Transcriptional enhancer factor TEF-4

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2