Anti-TEF-5 TEAD3 Antilichaam

Boster Bio Anti-TEF-5 TEAD3 Antibody catalog # A07748. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Transcriptional enhancer factor TEF-5; DTEF-1; TEA domain family member 3; TEAD-3; TEAD3; TEAD5, TEF5

TEAD3

Q99594

Human, Mouse, Rat

Recombinant fusion protein of human TEAD3 (NP_003205.2) .

Preferentially expressed in the placenta.

WB, IHC, ICC, IF

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

80 mg/mL by Refractometry

Liquid

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A07748

48676 MW

Transcriptional enhancer factor TEF-5

Nucleus.

Transcriptional enhancer factor TEF-5

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2