Anti-TGF-alfa (Transforming Growth Factor alpha) Monoklonale Antilichaam (Kloon: SPM357)

This antibody reacts with the C-terminus of TGF-alphaalpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGF-alpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

EGF-like TGF-alpha ETGF-alpha TFGA; TGF-alphaType 1; TGF-alpha; Wa1; Waved 1

TGF-alpha

7039

P01135

Human, Rat, Mouse

A 17-amino acid synthetic peptide from the carboxyl-terminus of rat TGF-alpha.

SPM357

FACS, IF

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

Flow Cytometry (1-2ug/million cells) ; Immunofluorescence (1-2ug/ml)

Mouse IgG1, kappa