Anti-THAP11 Antilichaam

The THAP domain-contining protein 11 (THAP11), also known as Ronin, is an essential factor involved in embryonic stem (ES) cell pluripotency and cell growth (1) . THAP 11 contains a THAP domain, a conserved DNA-binding domain common to many proteins associated with chromatin modification and gene expression silencing, and has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases (2) . THAP11 can also negatively regulate CD44 v6 expression through its interaction with the poly (rC) binding protein PCBP1 (3) .

Boster Bio Anti-THAP11 Antibody (Catalog # A08519) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

RONIN, CTG-B43a, CTG-B45d, HRIHFB2206, THAP domain-containing protein 11

THAP11

Q96EK4

Human, Mouse, Rat

THAP11 antibody is human, mouse and rat reactive.

THAP11 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THAP11. The immunogen is located within the last 50 amino acids of THAP11.

ELISA, WB

Stem Cells

THAP11 antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity) . .

THAP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

https://www.bosterbio.com/msds?sku=A08519

34455 MW

THAP domain containing 11

Nucleus

Bovine

THAP domain containing 11

IgG

THAP11 antibody is supplied in PBS containing 0.02% sodium azide.