Anti-THBS3 Antibody Picoband®

Thrombospondin-3 (TSP3) is a protein that in humans is encoded by the THBS3 gene. The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants.

Boster Bio Anti-THBS3 Antibody Picoband® catalog # A11652-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24

THBS3

7059

P49746

Human

No cross-reactivity with other proteins.

E.coli-derived human THBS3 recombinant protein (Position: Q23-T486) .

Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

WB, IHC, Flow Cytometry, ELISA

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

1. Adolph, K. W., Long, G. L., Winfield, S., Ginns, E. I., Bornstein, P. Structure and organization of the human thrombospondin 3 gene (THBS3) . Genomics 27: 329-336, 1995. 2. Bornstein, P., Devarayalu, S., Edelhoff, S., Disteche, C. M. Isolation and characterization of the mouse thrombospondin 3 (Thbs3) gene. Genomics 15: 607-613, 1993. 3. Bornstein, P., McKinney, C. E., LaMarca, M. E., Winfield, S., Shingu, T., Devarayalu, S., Vos, H. L., Ginns, E. I. Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease. Proc. Nat. Acad. Sci. 92: 4547-4551, 1995.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A11652-2

120 kDa

6

Eva-1 homolog A, regulator of programmed cell death

Endoplasmic reticulum membrane, Single-pass membrane protein, Lysosome membrane.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.