Anti-TIMM29 Antibody Picoband® 31.0647 Vervoeging

Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. Required for the stability of the TIM22 complex and functions in the assembly of the TIMM22 protein into the TIM22 complex. May facilitate cooperation between TIM22 and TOM complexes by interacting with TOMM40.

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

TIMM29

90580

Q9BSF4

Human

No cross-reactivity with other proteins.

E.coli-derived human TIMM29 recombinant protein (Position: A37-R260) .

Ubiquitously expressed.

Flow Cytometry

Chemokines, Immunology, Innate Immunity

Immunogen affinity purified.

Liquid

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

1. Callegari, S., Richter, F., Chojnacka, K., Jans, D. C., Lorenzi, I., Pacheu-Grau, D., Jakobs, S., Lenz, C., Urlaub, H., Dudek, J., Chacinska, A., Rehling, P. TIM29 is a subunit of the human carrier translocase required for protein transport. FEBS Lett. 590: 4147-4158, 2016. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 02/28/2017. 3. Kang, Y., Baker, M. J., Liem, M., Louber, J., McKenzie, M., Atukorala, I., Ang, C.-S., Keerthikumar, S., Mathivanan, S., Stojanovski, D. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. eLife 5: e17463, 2016. Note: Electronic Article.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

14377 MW

6

Retrotransposon Gag like 10

Cell membrane; Lipid-anchor, GPI-anchor.

Lymphocyte antigen 6A-2/6E-1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.