Anti-TLR9 Konijn Monoklonale Antilichaam

Boster Bio Anti-TLR9 Rabbit Monoclonal Antibody catalog # M00198. Tested in WB application. This antibody reacts with Human.

Toll-like receptor 9; CD289; TLR9; UNQ5798/PRO19605

TLR9

54106

Q9NR96

Human

A synthesized peptide derived from human TLR9

Clone: ABFH-20

Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre- dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.

WB

Adapters, Immunoglobulins, Immunology, Innate Immunity, Macrophage/Inflammation, Receptors, Signal Transduction, TLR Signaling, Transmembrane

Affinity-chromatography

0.5mg/ml

Liquid

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M00198

115860 MW

103 kDa

Toll-like receptor 9

Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endosome . Lysosome . Cytoplasmic vesicle, phagosome . Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. .

P2X purinoceptor 1

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.