Anti-TM9SF2 Antibody Picoband® fluoro488 Vervoeging

Transmembrane 9 superfamily member 2 is a protein that in humans is encoded by the TM9SF2 gene. This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome.

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

TM9SF2

9375

Q99805

Human, Rat

No cross-reactivity with other proteins

E.coli-derived human TM9SF2 recombinant protein (Position: R66-S596) .

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Flow Cytometry

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Liquid

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Diaz, E., Schimmoller, F., Pfeffer, S. R. A novel Rab9 effector required for endosome-to-TGN transport. J. Cell Biol. 138: 283-290, 1997. 2. Gross, M. B. Personal Communication. Baltimore, Md. 6/25/2014. 3. Schimmoller, F., Diaz, E., Muhlbauer, B., Pfeffer, S. R. Characterization of a 76 kDa endosomal, multispanning membrane protein that is highly conserved throughout evolution. Gene 216: 311-318, 1998.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

64099 MW

6

RNA-binding protein 47

Nucleus .

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.