Anti-TM9SF3 Antibody Picoband® fluoro488 Vervoeging

Predicted to be involved in protein localization to membrane. Predicted to be located in exocytic vesicle. Predicted to be active in membrane.

Mediator of RNA polymerase II transcription subunit 9; Mediator complex subunit 9; MED9; MED25

TM9SF3

56889

Q9HD45

Human

No cross-reactivity with other proteins.

E.coli-derived human TM9SF3 recombinant protein (Position: H31-M465) .

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Flow Cytometry

Epigenetics and Nuclear Signaling, Mediator Complex, Pol II Transcription, Polymerase Associated Factors, RNA Polymerase, Transcription

Immunogen affinity purified.

Liquid

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

1. Gross, M. B. Personal Communication. Baltimore, Md. 3/21/2016. 2. Sugasawa, T., Lenzen, G., Simon, S., Hidaka, J., Cahen, A., Guillaume, J.-L., Camoin, L., Strosberg, A. D., Nahmias, C. The iodocyanopindolol and SM-11044 binding protein belongs to the TM9SF multispanning membrane protein superfamily. Gene 273: 227-237, 2001.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Mediator complex subunit 9

Nucleus .

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.