Anti-TMEM173 Monoklonale Antilichaam

Boster Bio Anti-TMEM173 Monoclonal Antibody catalog # M01871. Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.

Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I; ADIPOR1; PAQR1 , TESBP1A; CGI-45

TMEM173

340061

Q86WV6

Human

A synthesized peptide derived from human TMEM173 Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta) . Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm.

Clone: AEAO-20

Widely expressed (PubMed:16044242) . Highly expressed in heart and skeletal muscle (PubMed:12802337) . Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337) . Weakly expressed in colon, thymus and small intestine (PubMed:12802337) . .

WB, ICC, IF, Flow Cytometry

Adapters, Antiviral Signaling, Cancer, Cytokines, Epigenetics and Nuclear Signaling, Immune System Diseases, Immunology, Innate Immunity, Interferons, NFKB Pathway, Nuclear Signaling Pathways, Signal Transduction, Transmembrane

Affinity-chromatography

0.5mg/ml

Liquid

Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:25855295, PubMed:12802337) . Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin (By similarity) . .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01871

42616 MW

90 kDa

Adiponectin receptor protein 1

Cell membrane ; Multi-pass membrane protein . Localized to the cell membrane and intracellular organelles. .

Lysosome-associated membrane glycoprotein 2 (Lamp2)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.