Anti-TMEM55B/PIP4P1 Antilichaam

TMEM55B is also named as C14orf9 and PIP4P1. TMEM55B is originally identified as phosphatidylinositol-4,5-P24-phosphatases (PtdIns-4,5-P24-phosphatases) that catalyze dephosphorylation of PtdIns-4,5-P2 to PtdIns-5-P. The transmembrane protein TMEM55B is involved in the perinuclear clustering of lysosomes upon starvation. TMEM55B expression is upregulated upon starvation via TFEB and TFE3 activation, and loss of TMEM55B diminishes starvation-induced lysosomal clustering. TMEM55B can bind to the dynein adaptor JIP4, promoting dynein-dynactin-dependent lysosomal trafficking to the perinuclear region. TMEM55B is also suggested to contribute to lysosomal homeostasis and mTORC1 activation via the V-ATPase assembly (PMID: 33537719) .

Boster Bio Anti-TMEM55B/PIP4P1 Antibody catalog # A12499. Tested in WB, IP, ELISA. This antibody reacts with Human, Mouse, Rat.

PIP4P1

Q86T03

Human, Mouse, Rat

E.coli-derived human TMEM55B/PIP4P1 recombinant protein (Position: G17-P80) .

WB, IP, ELISA

Immunogen affinity purified.

500 μg/mL

Liquid

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

https://www.bosterbio.com/datasheet?sku=A12499

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.