Anti-TMEM65 Antibody Picoband® 31.0550 Vervoeging

Predicted to be involved in cardiac ventricle development and regulation of cardiac conduction. Located in intercalated disc; mitochondrial inner membrane; and plasma membrane.

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

TMEM65

157378

Q6PI78

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence in the middle region of human TMEM65, identical to the related mouse sequences.

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Flow Cytometry

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Immunogen affinity purified.

Liquid

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

1. Hartz, P. A. Personal Communication. Baltimore, Md. 10/23/2015. 2. Nishimura, N., Gotoh, T., Oike, Y., Yano, M. TMEM65 is a mitochondrial inner-membrane protein. PeerJ 2: e349, 2014. Note: Electronic Article. 3. Sharma, P., Abbasi, C., Lazic, S., Teng, A. C. T., Wang, D., Dubois, N., Ignatchenko, V., Wong, V., Liu, J., Araki, T., Tiburcy, M., Ackerly, C., and 9 others. Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function. Nature Commun. 6: 8391, 2015. Note: Electronic Article.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

64099 MW

6

RNA-binding protein 47

Nucleus .

Follicular dendritic cell secreted peptide

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.