Anti-TOM1 Antilichaam Picoband® fluoro594 Vervoeging

Target of Myb protein 1 is a protein that in humans is encoded by the TOM1 gene. This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

TOM1

10043

O60784

Human

E.coli-derived human TOM1 recombinant protein (Position: R84-K480) . Human TOM1 shares 87.4% amino acid (aa) sequence identity with mouse TOM1.

Flow Cytometry

Immunogen affinity purified.

Liquid

1. Burk, O., Worpenberg, S., Haenig, B., Klempnauer, K. H. tom-1, a novel v-Myb target gene expressed in AMV- and E26-transformed myelomonocytic cells. EMBO J. 16: 1371-1380, 1997. 2. Katoh, Y., Imakagura, H., Futatsumori, M., Nakayama, K. Recruitment of clathrin onto endosomes by the Tom1-Tollip complex. Biochem. Biophys. Res. Commun. 341: 143-149, 2006. 3. Keskitalo, S., Haapaniemi, E. M., Glumoff, V., Liu, X., Lehtinen, V., Fogarty, C., Rajala, H., Chiang, S. C., Mustjoki, S., Kovanen, P., Lohi, J., Bryceson, Y. T., Seppanen, M., Kere, J., Heiskanen, K., Varjosalo, M. Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease. NPJ Genomic Med. 4: 14, 2019.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

54 kDa

6

IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.