Anti-TOM70 TOMM70 Antilichaam

The translocase of outer mitochondrial membrane (TOM) complex is a multisubunit complex involved in the recognition, unfolding, and translocation of preproteins into the mitochondria. TOM70, an important member of the TOM complex, contains a tetratricopeptide repeat domain similar to those found in cytosolic chaperones such as Hsp90 and Hsc70 and provides a docking site for these proteins. This interaction is thought to be a critical first step in the TOM70-dependent mitochondrial import, followed by contact between the preprotein and TOM70. After targeting to TOM70, preproteins are translocated through the outer membrane via the TOM40 import pore complex. The precise mechanism of how preproteins progress from TOM70 to TOM40 to full translocation is still unclear.

Boster Bio Anti-TOM70 TOMM70 Antibody (Catalog # A09172) . Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

KIAA0719, TOM70, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor

TOMM70A

O94826

Human, Mouse, Rat

At least two isoforms of TOM70 are known to exist; this antibody will only detect the larger isoform.

Anti-TOM70 antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human TOM70. The immunogen is located within amino acids 50-100 of TOM70.

Ubiquitous. Highly expressed in liver, kidney and muscle. Expressed at intermediate level in brain, heart, colon, thymus, kidney, small intestine, placenta, lung, leukocytes and spleen.

ELISA, WB, IHC-P, IF

Homeostasis

TOM70 Antibody is affinity chromatography purified via peptide column.

1 mg/mL

Liquid

Receptor that accelerates the import of all mitochondrial precursor proteins. .

TOM70 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

https://www.bosterbio.com/msds?sku=A09172

67455 MW

Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)

Mitochondrion outer membrane ; Single-pass membrane protein .

Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)

IgG

TOM70 Antibody is supplied in PBS containing 0.02% sodium azide.