Anti-TP53I13 Antibody Picoband®

TP53I13 is involved in several processes, including negative regulation of cell cycle, response to UV, and response to xenobiotic stimulus. It may act as a tumor suppressorwhich could inhibits tumor cell growth, when overexpressed.

Boster Bio Anti-TP53I13 Antibody Picoband® catalog # A16645-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Kelch repeat and BTB domain-containing protein 2; BTB and kelch domain-containing protein 1; KBTBD2; BKLHD1; KIAA1489

TP53I13

90313

Q8NBR0

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human TP53I13 recombinant protein (Position: A30-Q365) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

ELISA, IF, IHC, WB

Cell Biology

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.

1. Otsuki, T. , Ota, T. , Nishikawa, T. , Hayashi, K. , & Isogai, T. . (2005) . Signal sequence and keyword trap in silico for selection of full-length human cdnas encoding secretion or membrane proteins from oligo-capped cdna libraries. Dna Research, 12 (2), 117-126. 2. Luck, K. , Kim, D. K. , Lambourne, L. , Spirohn, K. , & Calderwood, M. A. . (2020) . A reference map of the human binary protein interactome. Nature, 580 (D1) . 3. Ota, T. , Suzuki, Y. , Nishikawa, T. , Otsuki, T. , Sugiyama, T. , & Irie, R. , et al. (2004) . Complete sequencing and characterization of 21,243 full-length human cdnas. Nature Genetics.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A16645-1

24145 MW

55 kDa

Kelch repeat and BTB domain containing 2

Cul3-RING ubiquitin ligase complex.

Transmembrane protein 240

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.