Anti-TRAM1 Antilichaam Picoband® fluoro550 Vervoeging

TRAM1 (Translocation-Associating Membrane Protein 1), By crosslinking and reconstitution of canine proteoliposomes, followed by microsequencing and PCR screening of canine kidney and HeLa cell cDNA libraries, Gorlich et al. (1992) isolated cDNAs encoding TRAM (translocating chain-associating membrane protein) . The International Radiation Hybrid Mapping Consortium mapped the TRAM gene to chromosome 8. Sequence analysis predicted that human TRAM is a 374-amino acid, 8-pass transmembrane protein that shares 95% amino acid identity with the canine protein. Functional analysis indicated that TRAM influences glycosylation and is stimulatory or required for the translocation of secretory proteins.

Translocating chain-associated membrane protein 1; TRAM1; TRAM

TRAM1

23471

Q15629

Human, Mouse, Rat

No cross-reactivity with other proteins

A synthetic peptide corresponding to a sequence at the C-terminus of human TRAM1, identical to the related rat and mouse sequences.

Flow Cytometry

Organelle Proteins, Organelles, Protein Trafficking, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Immunogen affinity purified.

Liquid

Stimulatory or required for the translocation of secretory proteins across the ER membrane.

1. Gorlich, D., Hartmann, E., Prehn, S., Rapoport, T. A. A protein of the endoplasmic reticulum involved early in polypeptide translocation. Nature 357: 47-52, 1992.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

43072 MW

No cross reactivity with other proteins.

6

Translocating chain-associated membrane protein 1

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Belongs to the TRAM family.

Translocating chain-associated membrane protein 1

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.