Anti-Trefoil factor 2 / TFF2 Monoklonale Antilichaam (Kloon: GE16C)

Trefoil peptides are protease resistant molecules secreted throμghout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thoμght to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

SML1; SP; Spasmolysin; Spasmolytic polypeptide; TFF2; trefoil factor 2 (spasmolytic protein 1) ; Trefoil factor 2; Trefoil factor 2 precursor

TFF2

7032

Q03403

Human

Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2.

GE16C

ELISA

200 μg/mL of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/mL.

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.

ELISA (For coating, order Ab without BSA & Azide)

Mouse IgM, kappa