Anti-TREML2 Antibody Picoband® 0,00647 Vervoeging

TREML2 is a single-pass type I membrane protein, and it contains 1 Ig-like V-type (immunoglobulin-like) domain. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties.

Pannexin-2; PANX2

TREML2

79865

Q5T2D2

Human

No cross-reactivity with other proteins.

E.coli-derived human TREML2 recombinant protein (Position: E64-I321) .

Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Flow Cytometry

Organelles, Subcellular Markers, Tags & Cell Markers

Immunogen affinity purified.

Liquid

Structural component of the gap junctions and the hemichannels.

1. Allcock, R. J. N., Barrow, A. D., Forbes, S., Beck, S., Trowsdale, J. The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. Europ. J. Immun. 33: 567-577, 2003. 2. Benitez, B. A., Jin, S. C., Guerreiro, R., Graham, R., Lord, J., Harold, D., Sims, R., Lambert, J.-C., Gibbs, J. R., Bras, J., Sassi, C., Harari, O., and 34 others. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol. Aging 35: e19-e26, 2014. Note: Electronic Article.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

6

Pannexin 2

Cell membrane. Multi-pass membrane protein. Gap junction.

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.