Anti-TRF1 TERF1 Konijn Monoklonale Antilichaam

Boster Bio Anti-TRF1 TERF1 Rabbit Monoclonal Antibody catalog # M02474. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Telomeric repeat-binding factor 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1; TERF1; PIN2, TRBF1, TRF, TRF1

TERF1

7013

P54274

Human, Mouse

A synthesized peptide derived from human TRF1

Clone: AOIB-20

Highly expressed and ubiquitous. Isoform Pin2 predominates.

WB, ICC, IF

Chromosome Structure, Epigenetics and Nuclear Signaling, Nucleus, Subcellular Markers, Tags & Cell Markers

Affinity-chromatography

0.5mg/ml

Liquid

Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double- stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M02474

50246 MW

48 kDa

Telomeric repeat-binding factor 1

Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, telomere. Colocalizes with telomeric DNA in interphase and prophase cells. Telomeric localization decreases in metaphase, anaphase and telophase. Associates with the mitotic spindle.

T-cell surface glycoprotein CD3 zeta chain

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.