Anti-TRIB3 Monoklonaal antilichaam

Boster Bio Anti-TRIB3 Monoclonal Antibody catalog # M01414. Tested in WB, IP applications. This antibody reacts with Human.

RalA-binding protein 1; RalBP1;76 kDa Ral-interacting protein; Dinitrophenyl S-glutathione ATPase; DNP-SG ATPase; Ral-interacting protein 1; RALBP1; RLIP1, RLIP76

TRIB3

57761

Q96RU7

Human

A synthesized peptide derived from human TRIB3 Disrupts insulin signaling by binding ly to Akt kinases and blocking their activation. May bind ly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.

Clone: AEIE-20

Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes. .

WB, IP

MAPK Pathway, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Affinity-chromatography

0.5mg/ml

Liquid

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin. .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=M01414

76063 MW

40 kDa

RalA-binding protein 1

Membrane ; Peripheral membrane protein .

Glycogen synthase kinase-3 beta (gsk3b)

Rabbit IgG

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.