Anti-TRIM3 Antibody Picoband®

Tripartite motif-containing protein 3 is a protein that in humans is encoded by the TRIM3 gene. The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified.

Boster Bio Anti-TRIM3 Antibody Picoband® catalog # A07081-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Ribosome-binding protein 1; 180 kDa ribosome receptor homolog; RRp; ES/130-related protein; Ribosome receptor protein; RRBP1; KIAA1398

TRIM3

10612

O75382

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human TRIM3 recombinant protein (Position: Q77-R433) .

Expressed in kidney.

WB, Flow Cytometry, ELISA

Cancer, DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, Translation, Tumor Biomarkers

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.

1. Cheung, C. C., Yang, C., Berger, T., Zaugg, K., Reilly, P., Elia, A. J., Wakeham, A., You-Ten, A., Chang, N., Li, L., Wan, Q., Mak, T. W. Identification of BERP (brain-expressed RING finger protein) as a p53 target gene that modulates seizure susceptibility through interacting with GABA (A) receptors. Proc. Nat. Acad. Sci. 107: 11883-11888, 2010. 2. El-Husseini, A. E., Kwasnicka, D., Yamada, T., Hirohashi, S., Vincent, S. R. BERP, a novel ring finger protein, binds to alpha-actinin-4. Biochem. Biophys. Res. Commun. 267: 906-911, 2000. 3. El-Husseini, A. E., Vincent, S. R. Cloning and characterization of a novel RING finger protein that interacts with class V myosins. J. Biol. Chem. 274: 19771-19777, 1999.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A07081-2

81 kDa

6

Ribosome binding protein 1

Endoplasmic reticulum membrane, Single-pass type III membrane protein.

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.