Anti-TRIP/TRAIP Antibody Picoband® fluoro647 Vervoeging

TRAF-interacting protein is a protein that in humans is encoded by the TRAIP gene. This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.

DAZ-associated protein 1; Deleted in azoospermia-associated protein 1; DAZAP1

TRAIP

10293

Q9BWF2

Human, Mouse, Rat

No cross-reactivity with other proteins.

E.coli-derived human TRIP/TRAIP recombinant protein (Position: M1-S469) .

Mainly expressed in testis. Expressed to a lower level in thymus. Weakly or not expressed in heart, liver, brain, placenta, lung, skeletal muscle, kidney and pancreas.

Flow Cytometry

Cancer, Cell Biology, Energy Metabolism, Energy Transfer Pathways, Metabolic Signaling Pathways, Metabolism, Oxidative Stress, Pathways and Processes, Redox Metabolism, Signal Transduction

Immunogen affinity purified.

Liquid

RNA-binding protein, which may be required during spermatogenesis.

1. Gross, M. B. Personal Communication. Baltimore, Md. 2/2/2016. 2. Harley, M. E., Murina, O., Leitch, A., Higgs, M. R., Bicknell, L. S., Yigit, G., Blackford, A. N., Zlatanou, A., Mackenzie, K. J., Reddy, K., Halachev, M., McGlasson, S., and 18 others. TRAIP promotes DNA damage response during genome replication and is mutated in primordial dwarfism. Nature Genet. 48: 36-43, 2016. 3. Lee, S. Y., Lee, S. Y., Choi, Y. TRAF-interacting protein (TRIP) : a novel component of the tumor necrosis factor receptor (TNFR) - and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappa-B activation. J. Exp. Med. 185: 1275-1285, 1997.

At -20 ̊C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

49229 MW

6

DAZ associated protein 1

Nucleus. Cytoplasm.

Chromaffin granule amine transporter

Rabbit IgG

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.