Anti-TRMT44 Antibody Picoband®

The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm. Defects in this gene may be a cause of partial epilepsy with pericentral spikes (PEPS), but that has not been proven definitively.

Boster Bio Anti-TRMT44 Antibody Picoband® catalog # A14732-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Transmembrane protein 199; TMEM199; C17orf32

TRMT44

152992

Q8IYL2

Human

No cross-reactivity with other proteins.

E.coli-derived human TRMT44 recombinant protein (Position: M1-S757) .

Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

WB, Flow Cytometry, ELISA

Cell Biology

Immunogen affinity purified.

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Lyophilized

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Accessory component of the proton-transporting vacuolar (V) -ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis.

1. Leschziner, G. D., Coffey, A. J., Andrew, T., Gregorio, S. P., Dias-Neto, E., Calafato, M., Bentley, D. R., Kinton, L., Sander, J. W., Johnson, M. R. Q81YL2 is a candidate gene for the familial epilepsy syndrome of partial epilepsy with pericentral spikes (PEPS) . Epilepsy Res. 96: 109-115, 2011.

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

https://www.bosterbio.com/msds?sku=A14732-1

64099 MW

85 kDa

6

Transmembrane protein 199

Endoplasmic reticulum membrane. Multi-pass membrane protein. COPI-coated vesicle membrane. Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane. Multi-pass membrane protein.

DAP3 binding cell death enhancer 1

Rabbit IgG

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.