Anti-TRMT61B Antilichaam

Boster Bio Anti-TRMT61B Antibody catalog # A12682. Tested in WB applications. This antibody reacts with Human.

TRNA (adenine (58) -N (1) ) -methyltransferase, mitochondrial;2.1.1.220

TRMT61B

Q9BVS5

Human

Recombinant fusion protein of human TRMT61B (NP_060380.3) .

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

1 mg/mL

Liquid

Methyltransferase that catalyzes the formation of N (1) - methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA (Leu) (deciphering codons UUA or UUG), tRNA (Lys) and tRNA (Ser) (deciphering codons UCA, UCU, UCG or UCC) (PubMed:23097428) . Catalyzes the formation of 1- methyladenosine at position 947 of mitochondrial 16S ribosomal RNA and this modification is most likely important for mitoribosomal structure and function (PubMed:27631568) . In addition to tRNA N (1) -methyltransferase activity, also acts as a mRNA N (1) - methyltransferase by mediating methylation of adenosine residues at the N (1) position of MT-ND5 mRNA, leading to interfere with mitochondrial translation (PubMed:29107537) .

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

https://www.bosterbio.com/msds?sku=A12682

52965 MW

WB: 1:500-1:2000

TRNA (adenine (58) -N (1) ) -methyltransferase, mitochondrial

Mitochondrion

TRNA (adenine (58) -N (1) ) -methyltransferase, mitochondrial

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2